Twitter has started to clearly mark spam accounts with this text: This account has been flagged as SPAM and has been frozen. It also looks like they’re removing the avatar (often semi-pornographic) and deleting the tweet history & Profile URL from these accounts so that the spammers can’t gain any Google juice from their frozen account. This will minimize some of the confusion that was occurring when you clicked the Profile URL from a New Follower email only to find that the account doesn’t exist because Twitter had already removed the spammy account.

Update:
So far, response to this latest tactic seems to be positive…

Update #2:
There is a similar message appearing for Suspended accounts…

The Suspended Accounts link is a Help page that describes why an account might be considered spammy. It also states that the account can be suspended because of Terms of Service violations. It’s not really clear to me yet what the difference is between an account that has been Frozen due to spam and an account that has been Suspended due to spammy behavior and/or TOS violations. Update: It appears that Twitter has changed their terminology in the last couple of days. They are no longer calling these accounts Frozen.
Here is the complete text of the Suspended Accounts help page:
A Twitter account may be suspended for a variety of reasons. The most common of which is automated mass following or other types of spammy behavior.
What is Spam on Twitter?
Commercial or promotional use of Twitter is allowed. There are many companies who create valuable, opt-in relationships with users on Twitter who want to keep up to date with them. However, if you are following other accounts in order to gain attention to your account or links therein, you may be considered spam. If you are creating a series of accounts in order to promote the same thing, you may be considered spam. If you are sending large numbers of @reply messages that are not genuine replies, you may be considered spam. If you are creating updates in order to show up in search results, you may be considered spam. If you are disguising links (i.e., writing about one thing but linking to another), you may be considered spam. If a large number of users have blocked you (relative to those following you), you may be considered spam.
Other Reasons Your Account May Be Suspended
It’s possible your account may be suspended for breaking other Twitter rules. Impersonation, illegal content, or any violation of the Twitter Terms of Service may result in the suspension of your account.
If You’ve Been Suspended Unjustly
Please let us know if you feel your account was suspended and you believe it should not be. We will review your request as soon as possible.
Update #3:
Biz Stone provides further explanation of the new Suspended accounts on the Twitter blog. He also provides some details on their anti-spam tactics: a new administration tool that makes it much easier for Twitter employees to identify and suspend spammy accounts and a full-time Spam Marshal starting next week. Here are some reactions to the news: